
The supply chain of biologics has been greatly challenged by the changing international environment and the Covid-19 epidemic. This situation has been exacerbated, especially this year, and caused project stagnation in many Russian biopharma companies and organizations. Finding a new and stable supply of upstream premium raw materials became very crucial for Russia Biopharma companies. Shanghai BioEngine Sci-Tech Co., LTD, one of the top cell culture medium suppliers in China, can provide the perfect solution for high-quality and cost-effective cell culture media products with a steady and safe supply from China.
With 30 years of experience in the fields of animal cell culture, BioEngine developed a series of serum-free cell culture media with independent IP for CHO cells, insect cells, HEK293 cells, Vero cells, MDCK cells, BHK cells, immune effector cells, other animal cells.


With a deep understanding of cell culture processes, the company has built up a leading-edge technical strength in the cell culture area and accomplished many breakthrough projects in China and even in the world. For examples:
Eden Series CHO CD Medium Eden series media are designed for high protein production by CHO cell lines such as CHO-K1, CHO-ZN, HORIZON, CHO-S, and CHO DG44 in a variety of culture processes including fed-batch, high cell density fed-batch, and perfusion.
High Product Yield and Quality Based on the statistical data of over 100 customer projects, the maximum titer of fed-batch culture reaches14 g/L on day 14. The average titer is 20% higher than that of the best-performing imported brand, and the critical quality attributes are consistently comparable with the original drugs, which can effectively reduce costs and increase efficiency for biopharmaceutical enterprises.
High Safety and compliance No cytokines, antibiotics, hormones, and animal-derived components eliminate the risk of various external factor pollution. High-quality raw materials and internationally certified multi-quality systems ensure product safety and quality.
Celer series serum-free media are developed to support the rapid cell growth and high cell-density culture and promote adenovirus or protein production of various 293 cell lines, such as HEK293, 293T, and 293F cells. It is suitable for virology research, adenovirus vector (such as the COVID-19 vaccine), and other large-scale industrial production. It has been successfully applied to kilo-liter scale bioreactor production and has served customer projects for IND.
HIPP-T009 is an ideal choice for large-scale culture of lymphocytes. It demonstrates excellent performance on cell expansion and functional expression and ensures high safety and stability of the culture process since no serum or other serum substitutes are needed in the culturing system. As HIPP-T009 contains no exogenous cytokines or activators, corresponding cytokines or activators should be added if necessary.
Shanghai BioEngine Sci-Tech Co., LTD was founded on December 24, 2014, in Shanghai China. It provides high-quality & cost-effective cell culture media and professional technical services in antibody, vaccine, and cell & gene therapy fields. The headquarter and R&D center are in Shanghai Zhangjiang Hi-Tech Park, and the Phase II production base (Shanghai Beijin Biotech Co., Ltd.) is in Jinshan, Shanghai.

Beijin Biotech Co., Ltd., a wholly owned subsidiary and supply chain center of BioEngine, has completed large-scale, informatization and internationalization construction, and became a world-class culture medium factory "based in Shanghai and serving the world".